HCSGD entry for KLF8
1. General information
| Official gene symbol | KLF8 |
|---|---|
| Entrez ID | 11279 |
| Gene full name | Kruppel-like factor 8 |
| Other gene symbols | BKLF3 ZNF741 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5675107329 | 0.3648411307 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0164685718 |
| GSE13712_SHEAR | Down | -1.6877548989 |
| GSE13712_STATIC | Down | -0.0338792027 |
| GSE19018 | Up | 0.1373321558 |
| GSE19899_A1 | Up | 0.0427672861 |
| GSE19899_A2 | Down | -0.0362384664 |
| PubMed_21979375_A1 | Up | 0.1478523054 |
| PubMed_21979375_A2 | Up | 0.0070035874 |
| GSE35957 | Down | -0.1327015778 |
| GSE36640 | Up | 0.3938791701 |
| GSE54402 | Up | 0.1599181599 |
| GSE9593 | Down | -0.0428168473 |
| GSE43922 | Up | 0.0123988973 |
| GSE24585 | Up | 0.2913899671 |
| GSE37065 | Up | 0.1564760574 |
| GSE28863_A1 | Down | -0.3199965344 |
| GSE28863_A2 | Up | 0.0288984059 |
| GSE28863_A3 | Up | 0.2107096730 |
| GSE28863_A4 | Down | -0.0056395590 |
| GSE48662 | Down | -0.0554619278 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017467 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
