HCSGD entry for SP140
1. General information
| Official gene symbol | SP140 |
|---|---|
| Entrez ID | 11262 |
| Gene full name | SP140 nuclear body protein |
| Other gene symbols | LYSP100 LYSP100-A LYSP100-B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005635 | Nuclear envelope | TAS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0006952 | Defense response | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:2001141 | Regulation of RNA biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0013684738 | 0.9649013297 | 0.0996610497 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1380091131 |
| GSE13712_SHEAR | Up | 0.2204570285 |
| GSE13712_STATIC | Up | 0.1099710569 |
| GSE19018 | Down | -0.0067681628 |
| GSE19899_A1 | Up | 0.3775761469 |
| GSE19899_A2 | Up | 4.0316489587 |
| PubMed_21979375_A1 | Up | 4.9769362876 |
| PubMed_21979375_A2 | Up | 5.4463114891 |
| GSE35957 | Down | -0.0599721254 |
| GSE36640 | Up | 0.3476092614 |
| GSE54402 | Up | 1.4502668604 |
| GSE9593 | Up | 0.2216008045 |
| GSE43922 | Up | 1.8756688161 |
| GSE24585 | Down | -0.0213806734 |
| GSE37065 | Down | -0.0657361867 |
| GSE28863_A1 | Down | -0.0369678613 |
| GSE28863_A2 | Up | 0.3802827300 |
| GSE28863_A3 | Down | -0.4289235029 |
| GSE28863_A4 | Down | -0.2600226944 |
| GSE48662 | Up | 0.0263822457 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
