HCSGD entry for PTGDR2

1. General information

Official gene symbolPTGDR2
Entrez ID11251
Gene full nameprostaglandin D2 receptor 2
Other gene symbolsCD294 CRTH2 DL1R DP2 GPR44
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001785Prostaglandin J receptor activityIEAmolecular_function
GO:0004930G-protein coupled receptor activityIDAmolecular_function
GO:0004956Prostaglandin D receptor activityIDAmolecular_function
GO:0004958Prostaglandin F receptor activityIEAmolecular_function
GO:0004982N-formyl peptide receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006935ChemotaxisIDAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIDAbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0019722Calcium-mediated signalingIDAbiological_process
GO:0045745Positive regulation of G-protein coupled receptor protein signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26971083170.89041259070.96677908211.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1121428256
GSE13712_SHEARDown-0.0329565773
GSE13712_STATICDown-0.0356772652
GSE19018Up0.1214668654
GSE19899_A1Up0.0620372267
GSE19899_A2Up0.0369719538
PubMed_21979375_A1Up0.3463844615
PubMed_21979375_A2Down-0.0935986702
GSE35957Up0.2220724289
GSE36640Up0.0939633322
GSE54402Up0.0298827798
GSE9593Down-0.0397023031
GSE43922Down-0.0068862050
GSE24585Up0.0709976671
GSE37065Down-0.0292315341
GSE28863_A1Up0.0924738788
GSE28863_A2Up0.0616945965
GSE28863_A3Up0.8504642859
GSE28863_A4Up0.0056848581
GSE48662Up0.0317669966

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

IndomethacinDB00328 APRD00109
ZomepiracDB04828 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.