HCSGD entry for ZHX1
1. General information
| Official gene symbol | ZHX1 |
|---|---|
| Entrez ID | 11244 |
| Gene full name | zinc fingers and homeoboxes 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0003714 | Transcription corepressor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9932780631 | 0.0077770221 | 0.9999902473 | 0.1764646552 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3387697509 |
| GSE13712_SHEAR | Up | 0.0942840639 |
| GSE13712_STATIC | Down | -0.0511168799 |
| GSE19018 | Down | -0.7588692332 |
| GSE19899_A1 | Down | -0.7546161855 |
| GSE19899_A2 | Down | -1.2002443571 |
| PubMed_21979375_A1 | Down | -0.7727328514 |
| PubMed_21979375_A2 | Down | -0.7255924622 |
| GSE35957 | Up | 0.0523171196 |
| GSE36640 | Up | 0.2525330807 |
| GSE54402 | Down | -0.9347702318 |
| GSE9593 | Down | -0.1938898628 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.5821268452 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT002558 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027040 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028258 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
