HCSGD entry for CHN2

1. General information

Official gene symbolCHN2
Entrez ID1124
Gene full namechimerin 2
Other gene symbolsARHGAP3 BCH CHN2-3 RHOGAP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005070SH3/SH2 adaptor activityTASmolecular_function
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0009967Positive regulation of signal transductionTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0043085Positive regulation of catalytic activityTASbiological_process
GO:0043547Positive regulation of GTPase activityTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67031251850.57712698230.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0354433193
GSE13712_SHEARDown-0.3813820028
GSE13712_STATICDown-0.1902139382
GSE19018Down-0.0011956295
GSE19899_A1Up0.0950466913
GSE19899_A2Down-0.0044599056
PubMed_21979375_A1Up0.0035300592
PubMed_21979375_A2Down-0.0267081480
GSE35957Up0.6451353280
GSE36640Down-0.1601088812
GSE54402Down-0.0438374092
GSE9593Down-0.0598494026
GSE43922Up0.0102069328
GSE24585Down-0.1366975334
GSE37065Down-0.0241490179
GSE28863_A1Down-0.1170193879
GSE28863_A2Up0.0373657837
GSE28863_A3Up0.1588654790
GSE28863_A4Up0.2048401776
GSE48662Up0.0977003600

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.