HCSGD entry for RNF139

1. General information

Official gene symbolRNF139
Entrez ID11236
Gene full namering finger protein 139
Other gene symbolsHRCA1 RCA1 TRC8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIDA IMPmolecular_function
GO:0004872Receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008285Negative regulation of cell proliferationIDAbiological_process
GO:0016021Integral component of membraneTAScellular_component
GO:0016567Protein ubiquitinationIDA IMPbiological_process
GO:0016874Ligase activityTASmolecular_function
GO:0017148Negative regulation of translationIDAbiological_process
GO:0019787Small conjugating protein ligase activityIDAmolecular_function
GO:0031396Regulation of protein ubiquitinationIDAbiological_process
GO:0060628Regulation of ER to Golgi vesicle-mediated transportIDAbiological_process
GO:0070613Regulation of protein processingIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07568035030.94911200180.58220525701.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0842145504
GSE13712_SHEARUp0.0496302146
GSE13712_STATICUp0.0819841488
GSE19018Up0.1236856121
GSE19899_A1Up0.5890978438
GSE19899_A2Up0.1938453909
PubMed_21979375_A1Up0.7045015520
PubMed_21979375_A2Up0.3986556944
GSE35957Up0.1258815539
GSE36640Down-0.0784487192
GSE54402Up0.0966465058
GSE9593Up0.0852886284
GSE43922Up0.2339627254
GSE24585Up0.3184257563
GSE37065Up0.0488090911
GSE28863_A1Up0.1195657106
GSE28863_A2Up0.3911607691
GSE28863_A3Down-0.6593944401
GSE28863_A4Down-0.1644903853
GSE48662Up0.0370093913

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-423-5pMIMAT0004748MIRT038108CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.