HCSGD entry for CHML
1. General information
| Official gene symbol | CHML |
|---|---|
| Entrez ID | 1122 |
| Gene full name | choroideremia-like (Rab escort protein 2) |
| Other gene symbols | REP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004663 | Rab geranylgeranyltransferase activity | IEA | molecular_function |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005968 | Rab-protein geranylgeranyltransferase complex | IMP | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0017137 | Rab GTPase binding | IDA IPI | molecular_function |
| GO:0018344 | Protein geranylgeranylation | IDA IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9892444284 | 0.0123560845 | 0.9999902473 | 0.2194385705 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4682280368 |
| GSE13712_SHEAR | Up | 0.2348078096 |
| GSE13712_STATIC | Up | 0.2529412935 |
| GSE19018 | Down | -0.0385544996 |
| GSE19899_A1 | Down | -0.3447277771 |
| GSE19899_A2 | Down | -0.6412132078 |
| PubMed_21979375_A1 | Up | 0.1667623554 |
| PubMed_21979375_A2 | Down | -0.0929310317 |
| GSE35957 | Down | -0.0017113076 |
| GSE36640 | Down | -0.5467485901 |
| GSE54402 | Down | -0.1313043919 |
| GSE9593 | Down | -0.2134519555 |
| GSE43922 | Down | -0.8829259781 |
| GSE24585 | Down | -0.0566694343 |
| GSE37065 | Down | -0.2478020652 |
| GSE28863_A1 | Down | -0.3988938853 |
| GSE28863_A2 | Down | -0.1062251133 |
| GSE28863_A3 | Down | -0.4551883912 |
| GSE28863_A4 | Down | -0.3818935259 |
| GSE48662 | Down | -0.4645889087 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024645 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026340 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027563 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027897 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
