HCSGD entry for KLK8
1. General information
| Official gene symbol | KLK8 |
|---|---|
| Entrez ID | 11202 |
| Gene full name | kallikrein-related peptidase 8 |
| Other gene symbols | HNP NP NRPN PRSS19 TADG14 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | ISS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007613 | Memory | ISS | biological_process |
| GO:0008219 | Cell death | ISS | biological_process |
| GO:0009611 | Response to wounding | ISS | biological_process |
| GO:0031642 | Negative regulation of myelination | ISS | biological_process |
| GO:0043616 | Keratinocyte proliferation | ISS | biological_process |
| GO:0048681 | Negative regulation of axon regeneration | ISS | biological_process |
| GO:0048812 | Neuron projection morphogenesis | ISS | biological_process |
| GO:0050807 | Regulation of synapse organization | ISS | biological_process |
| GO:0050808 | Synapse organization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8300412902 | 0.7558821967 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0776256215 |
| GSE13712_SHEAR | Down | -0.0025628191 |
| GSE13712_STATIC | Down | -0.1091889267 |
| GSE19018 | Up | 0.0254462258 |
| GSE19899_A1 | Up | 0.1125156691 |
| GSE19899_A2 | Up | 0.1074153287 |
| PubMed_21979375_A1 | Down | -0.1966571598 |
| PubMed_21979375_A2 | Down | -0.0950454580 |
| GSE35957 | Up | 0.1241982819 |
| GSE36640 | Up | 0.0745023208 |
| GSE54402 | Down | -0.1242623988 |
| GSE9593 | Up | 0.0953076939 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.1896021252 |
| GSE28863_A2 | Down | -0.0949889602 |
| GSE28863_A3 | Down | -0.0274536978 |
| GSE28863_A4 | Up | 0.1158464069 |
| GSE48662 | Down | -0.0857090198 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
