HCSGD entry for CHKB
1. General information
| Official gene symbol | CHKB |
|---|---|
| Entrez ID | 1120 |
| Gene full name | choline kinase beta |
| Other gene symbols | CHETK CHKL CK CKB CKEKB EK EKB MDCMC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004103 | Choline kinase activity | IDA | molecular_function |
| GO:0004305 | Ethanolamine kinase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006646 | Phosphatidylethanolamine biosynthetic process | IDA IEA TAS | biological_process |
| GO:0006656 | Phosphatidylcholine biosynthetic process | TAS | biological_process |
| GO:0006657 | CDP-choline pathway | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9779135177 | 0.0406366058 | 0.9999902473 | 0.3802230387 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1034348340 |
| GSE13712_SHEAR | Down | -0.6794227849 |
| GSE13712_STATIC | Down | -0.2023090561 |
| GSE19018 | Up | 0.1168661098 |
| GSE19899_A1 | Down | -0.3355259261 |
| GSE19899_A2 | Down | -1.2990604339 |
| PubMed_21979375_A1 | Down | -0.3019498727 |
| PubMed_21979375_A2 | Down | -0.0194031984 |
| GSE35957 | Down | -0.5171982598 |
| GSE36640 | Up | 0.3295006964 |
| GSE54402 | Down | -0.3167292187 |
| GSE9593 | Down | -0.3508163054 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.0958602932 |
| GSE28863_A2 | Up | 0.1246597708 |
| GSE28863_A3 | Up | 0.0178393008 |
| GSE28863_A4 | Up | 0.0260438961 |
| GSE48662 | Down | -0.3565172914 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
