HCSGD entry for SUPT16H
1. General information
| Official gene symbol | SUPT16H |
|---|---|
| Entrez ID | 11198 |
| Gene full name | suppressor of Ty 16 homolog (S. cerevisiae) |
| Other gene symbols | CDC68 FACTP140 SPT16/CDC68 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0006260 | DNA replication | IEA | biological_process |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006337 | Nucleosome disassembly | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0032786 | Positive regulation of DNA-templated transcription, elongation | TAS | biological_process |
| GO:0050434 | Positive regulation of viral transcription | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2200383040 | 0.0487084381 | 0.9019175229 | 0.4128161571 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2423724408 |
| GSE13712_SHEAR | Up | 0.0933810115 |
| GSE13712_STATIC | Down | -0.2290939542 |
| GSE19018 | Down | -0.2464202613 |
| GSE19899_A1 | Down | -0.1355569169 |
| GSE19899_A2 | Down | -1.1377648215 |
| PubMed_21979375_A1 | Up | 0.1826156508 |
| PubMed_21979375_A2 | Down | -0.3460133674 |
| GSE35957 | Down | -0.4730093786 |
| GSE36640 | Down | -1.5210051772 |
| GSE54402 | Up | 0.0830931644 |
| GSE9593 | Up | 0.0158824908 |
| GSE43922 | Down | -0.1316837190 |
| GSE24585 | Down | -0.0592177930 |
| GSE37065 | Down | -0.0922980005 |
| GSE28863_A1 | Up | 0.5983414121 |
| GSE28863_A2 | Up | 0.9632957932 |
| GSE28863_A3 | Up | 0.3551765427 |
| GSE28863_A4 | Up | 0.0962350441 |
| GSE48662 | Down | -0.8962592232 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031692 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037170 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038337 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039995 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040787 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041946 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042786 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT044101 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045114 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050293 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051819 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052127 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
