HCSGD entry for NISCH
1. General information
| Official gene symbol | NISCH |
|---|---|
| Entrez ID | 11188 |
| Gene full name | nischarin |
| Other gene symbols | I-1 IR1 IRAS hIRAS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005178 | Integrin binding | IEA | molecular_function |
| GO:0005769 | Early endosome | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006006 | Glucose metabolic process | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007154 | Cell communication | IEA | biological_process |
| GO:0008217 | Regulation of blood pressure | IEA | biological_process |
| GO:0008227 | G-protein coupled amine receptor activity | IEA | molecular_function |
| GO:0016601 | Rac protein signal transduction | IEA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IEA | biological_process |
| GO:0030336 | Negative regulation of cell migration | IEA | biological_process |
| GO:0032228 | Regulation of synaptic transmission, GABAergic | IEA | biological_process |
| GO:0035091 | Phosphatidylinositol binding | IEA | molecular_function |
| GO:0048243 | Norepinephrine secretion | IEA | biological_process |
| GO:0055037 | Recycling endosome | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4521943277 | 0.2365583792 | 0.9999902473 | 0.9365289731 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0577299522 |
| GSE13712_SHEAR | Down | -0.2945699801 |
| GSE13712_STATIC | Down | -0.0270630449 |
| GSE19018 | Up | 0.0649656590 |
| GSE19899_A1 | Down | -0.4576064749 |
| GSE19899_A2 | Down | -0.1368944377 |
| PubMed_21979375_A1 | Up | 0.1786782210 |
| PubMed_21979375_A2 | Up | 0.2233842381 |
| GSE35957 | Up | 0.0514530724 |
| GSE36640 | Up | 0.7125637242 |
| GSE54402 | Down | -0.2308263670 |
| GSE9593 | Down | -0.0640975559 |
| GSE43922 | Down | -0.2453299297 |
| GSE24585 | Up | 0.2152092631 |
| GSE37065 | Down | -0.3101216414 |
| GSE28863_A1 | Up | 0.4614415119 |
| GSE28863_A2 | Up | 0.2361862722 |
| GSE28863_A3 | Down | -0.2776254776 |
| GSE28863_A4 | Down | -0.2891893984 |
| GSE48662 | Up | 0.7121218756 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-455-3p | MIMAT0004784 | MIRT037847 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051287 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
