HCSGD entry for WDR6
1. General information
| Official gene symbol | WDR6 |
|---|---|
| Entrez ID | 11180 |
| Gene full name | WD repeat domain 6 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007050 | Cell cycle arrest | IDA | biological_process |
| GO:0008180 | COP9 signalosome | IDA | cellular_component |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0010507 | Negative regulation of autophagy | IMP | biological_process |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0043560 | Insulin receptor substrate binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7269105581 | 0.1197768588 | 0.9999902473 | 0.6651126977 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1064425300 |
| GSE13712_SHEAR | Down | -0.2831922025 |
| GSE13712_STATIC | Down | -0.1578338257 |
| GSE19018 | Down | -0.2224858031 |
| GSE19899_A1 | Down | -0.0775918477 |
| GSE19899_A2 | Down | -0.4848280445 |
| PubMed_21979375_A1 | Down | -0.3057565744 |
| PubMed_21979375_A2 | Up | 0.5608105861 |
| GSE35957 | Down | -0.1576988973 |
| GSE36640 | Down | -0.1302217521 |
| GSE54402 | Down | -0.0248322937 |
| GSE9593 | Down | -0.2619829119 |
| GSE43922 | Down | -0.2059959838 |
| GSE24585 | Up | 0.1206592995 |
| GSE37065 | Down | -0.1620563244 |
| GSE28863_A1 | Up | 0.6849078891 |
| GSE28863_A2 | Up | 0.2810500537 |
| GSE28863_A3 | Down | -0.3169645862 |
| GSE28863_A4 | Down | -0.2972205310 |
| GSE48662 | Up | 0.0159547965 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT003823 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-760 | MIMAT0004957 | MIRT036730 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039347 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040119 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046727 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-107 | MIMAT0000104 | MIRT048308 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049150 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052587 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
