HCSGD entry for ADAMTS6
1. General information
| Official gene symbol | ADAMTS6 |
|---|---|
| Entrez ID | 11174 |
| Gene full name | ADAM metallopeptidase with thrombospondin type 1 motif, 6 |
| Other gene symbols | ADAM-TS 6 ADAM-TS6 ADAMTS-6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008237 | Metallopeptidase activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7905162988 | 0.0196541355 | 0.9999902473 | 0.2729902375 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.8719014975 |
| GSE13712_SHEAR | Down | -0.6655735355 |
| GSE13712_STATIC | Down | -0.2535113302 |
| GSE19018 | Up | 0.4185916073 |
| GSE19899_A1 | Up | 0.0948864425 |
| GSE19899_A2 | Down | -0.1165348258 |
| PubMed_21979375_A1 | Up | 0.9408782289 |
| PubMed_21979375_A2 | Down | -0.1850217781 |
| GSE35957 | Down | -0.0987807755 |
| GSE36640 | Down | -2.4868007026 |
| GSE54402 | Down | -0.3404071352 |
| GSE9593 | Down | -0.4133832195 |
| GSE43922 | Down | -0.1436477258 |
| GSE24585 | Up | 0.1104259131 |
| GSE37065 | Up | 0.4147754396 |
| GSE28863_A1 | Down | -0.0880129150 |
| GSE28863_A2 | Up | 0.1781808817 |
| GSE28863_A3 | Down | -0.0995346888 |
| GSE28863_A4 | Down | -0.3911612265 |
| GSE48662 | Down | -0.4630554561 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019293 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
