HCSGD entry for ADAMTS7


1. General information

Official gene symbolADAMTS7
Entrez ID11173
Gene full nameADAM metallopeptidase with thrombospondin type 1 motif, 7
Other gene symbolsADAM-TS 7 ADAM-TS7 ADAMTS-7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0008237Metallopeptidase activityTASmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009986Cell surfaceIEAcellular_component
GO:0032331Negative regulation of chondrocyte differentiationIDAbiological_process
GO:0051603Proteolysis involved in cellular protein catabolic processIMPbiological_process
GO:0071347Cellular response to interleukin-1IMPbiological_process
GO:0071356Cellular response to tumor necrosis factorIMPbiological_process
GO:0071773Cellular response to BMP stimulusIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54692229780.47074341020.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1761348310
GSE13712_SHEARDown-0.3461352526
GSE13712_STATICDown-0.1707307465
GSE19018Up0.0499721328
GSE19899_A1Down-0.0546637554
GSE19899_A2Up0.1207961110
PubMed_21979375_A1Down-0.0755587167
PubMed_21979375_A2Up0.0683541012
GSE35957Up0.1411785535
GSE36640Up0.0194685644
GSE54402Down-0.0336759511
GSE9593Down-0.0005573886
GSE43922Up0.0840141443
GSE24585Up0.3591165878
GSE37065Down-0.2012965072
GSE28863_A1Down-0.1988653272
GSE28863_A2Down-0.1649586351
GSE28863_A3Up0.1319034982
GSE28863_A4Up0.1249236572
GSE48662Up0.7068101625

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.