HCSGD entry for STRAP
1. General information
| Official gene symbol | STRAP |
|---|---|
| Entrez ID | 11171 |
| Gene full name | serine/threonine kinase receptor associated protein |
| Other gene symbols | MAWD PT-WD UNRIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0000387 | Spliceosomal snRNP assembly | IDA | biological_process |
| GO:0005102 | Receptor binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005681 | Spliceosomal complex | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0030054 | Cell junction | IDA | cellular_component |
| GO:0030512 | Negative regulation of transforming growth factor beta receptor signaling pathway | IEA TAS | biological_process |
| GO:0032797 | SMN complex | IDA | cellular_component |
| GO:0034719 | SMN-Sm protein complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9092703621 | 0.4239165381 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0907399882 |
| GSE13712_SHEAR | Down | -0.1088504674 |
| GSE13712_STATIC | Down | -0.0438061318 |
| GSE19018 | Down | -0.0432468904 |
| GSE19899_A1 | Up | 0.0890385258 |
| GSE19899_A2 | Up | 0.0194407439 |
| PubMed_21979375_A1 | Up | 0.1680983129 |
| PubMed_21979375_A2 | Up | 0.1050861516 |
| GSE35957 | Down | -0.0940298093 |
| GSE36640 | Down | -0.1455741803 |
| GSE54402 | Up | 0.1353682935 |
| GSE9593 | Down | -0.0572778861 |
| GSE43922 | Down | -0.0020323013 |
| GSE24585 | Down | -0.2055243654 |
| GSE37065 | Down | -0.1233829287 |
| GSE28863_A1 | Up | 0.0505173669 |
| GSE28863_A2 | Down | -0.1321522465 |
| GSE28863_A3 | Up | 0.0154750132 |
| GSE28863_A4 | Up | 0.1251239168 |
| GSE48662 | Down | -0.2941403378 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025462 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031678 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-374b-5p | MIMAT0004955 | MIRT036801 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
