HCSGD entry for SOX21


1. General information

Official gene symbolSOX21
Entrez ID11166
Gene full nameSRY (sex determining region Y)-box 21
Other gene symbolsSOX25
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000981Sequence-specific DNA binding RNA polymerase II transcription factor activityNASmolecular_function
GO:0001942Hair follicle developmentIEAbiological_process
GO:0003677DNA bindingISSmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityISSmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005634NucleusIEAcellular_component
GO:0006355Regulation of transcription, DNA-templatedISSbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterNASbiological_process
GO:0006366Transcription from RNA polymerase II promoterNASbiological_process
GO:0048863Stem cell differentiationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38147687400.81237555180.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0065170698
GSE13712_SHEARUp0.1222840677
GSE13712_STATICDown-0.0004473829
GSE19018Up0.1163482802
GSE19899_A1Up0.0028200801
GSE19899_A2Up0.0736064765
PubMed_21979375_A1Up0.3318407316
PubMed_21979375_A2Up0.1743514497
GSE35957Up0.1059714960
GSE36640Up0.0509565405
GSE54402Down-0.0400013833
GSE9593Up0.1184368078
GSE43922Up0.0514657579
GSE24585Down-0.1156074386
GSE37065Down-0.0637861241
GSE28863_A1Down-0.1808399352
GSE28863_A2Down-0.2665105046
GSE28863_A3Up0.5646851651
GSE28863_A4Up0.0579291123
GSE48662Up0.0358506595

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.