HCSGD entry for ERLIN2
1. General information
| Official gene symbol | ERLIN2 |
|---|---|
| Entrez ID | 11160 |
| Gene full name | ER lipid raft associated 2 |
| Other gene symbols | C8orf2 Erlin-2 NET32 SPFH2 SPG18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0043234 | Protein complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9095976521 | 0.0873037461 | 0.9999902473 | 0.5604687561 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2273225630 |
| GSE13712_SHEAR | Down | -0.5581791260 |
| GSE13712_STATIC | Up | 0.0539602564 |
| GSE19018 | Up | 0.2355895741 |
| GSE19899_A1 | Down | -0.3429502659 |
| GSE19899_A2 | Down | -0.3380079082 |
| PubMed_21979375_A1 | Down | -0.7629369019 |
| PubMed_21979375_A2 | Down | -0.3004697860 |
| GSE35957 | Up | 0.0880441427 |
| GSE36640 | Up | 0.1239923656 |
| GSE54402 | Down | -0.5712356116 |
| GSE9593 | Up | 0.1683045158 |
| GSE43922 | Down | -0.2353886511 |
| GSE24585 | Down | -0.0394532871 |
| GSE37065 | Down | -0.1136887954 |
| GSE28863_A1 | Up | 0.1496630660 |
| GSE28863_A2 | Up | 0.4397149123 |
| GSE28863_A3 | Up | 0.0155547215 |
| GSE28863_A4 | Down | -0.0145288976 |
| GSE48662 | Up | 0.0117627301 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT004154 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025281 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031903 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-326 | MIMAT0000756 | MIRT043639 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047981 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048896 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
