HCSGD entry for WDR45
1. General information
| Official gene symbol | WDR45 |
|---|---|
| Entrez ID | 11152 |
| Gene full name | WD repeat domain 45 |
| Other gene symbols | NBIA4 NBIA5 WDRX1 WIPI-4 WIPI4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000045 | Autophagic vacuole assembly | IBA | biological_process |
| GO:0005083 | Small GTPase regulator activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0006914 | Autophagy | IMP | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0032266 | Phosphatidylinositol-3-phosphate binding | IBA | molecular_function |
| GO:0080025 | Phosphatidylinositol-3,5-bisphosphate binding | IBA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0014063675 | 0.9973758292 | 0.1010823848 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3238762987 |
| GSE13712_SHEAR | Up | 0.9521213772 |
| GSE13712_STATIC | Up | 0.0219589880 |
| GSE19018 | Up | 0.1996490961 |
| GSE19899_A1 | Up | 1.0425361475 |
| GSE19899_A2 | Up | 1.6867984104 |
| PubMed_21979375_A1 | Up | 2.4784375597 |
| PubMed_21979375_A2 | Up | 1.9171285975 |
| GSE35957 | Up | 0.0234584487 |
| GSE36640 | Up | 0.5174476366 |
| GSE54402 | Up | 0.6190683557 |
| GSE9593 | Up | 0.3108011375 |
| GSE43922 | Up | 0.6873308682 |
| GSE24585 | Up | 0.3011927718 |
| GSE37065 | Up | 0.0514215451 |
| GSE28863_A1 | Up | 0.0723002283 |
| GSE28863_A2 | Up | 0.1650603608 |
| GSE28863_A3 | Down | -0.0519904529 |
| GSE28863_A4 | Down | -0.0056770911 |
| GSE48662 | Up | 0.1285456519 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025809 | Microarray | Functional MTI (Weak) | 19073608 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
