HCSGD entry for CORO1A

1. General information

Official gene symbolCORO1A
Entrez ID11151
Gene full namecoronin, actin binding protein, 1A
Other gene symbolsCLABP CLIPINA HCORO1 TACO p57
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001772Immunological synapseIEAcellular_component
GO:0001845Phagolysosome assemblyIMPbiological_process
GO:0001891Phagocytic cupIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005884Actin filamentIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006816Calcium ion transportIEAbiological_process
GO:0006909PhagocytosisIMPbiological_process
GO:0006928Cellular component movementNASbiological_process
GO:0007015Actin filament organizationIEAbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0008092Cytoskeletal protein bindingISSmolecular_function
GO:0008360Regulation of cell shapeIBA IEAbiological_process
GO:0015629Actin cytoskeletonIEAcellular_component
GO:0030027LamellipodiumIDAcellular_component
GO:0030036Actin cytoskeleton organizationIEA IMPbiological_process
GO:0030335Positive regulation of cell migrationIEAbiological_process
GO:0030595Leukocyte chemotaxisIBA IEAbiological_process
GO:0030670Phagocytic vesicle membraneIEAcellular_component
GO:0030833Regulation of actin filament polymerizationIEAbiological_process
GO:0030864Cortical actin cytoskeletonIDAcellular_component
GO:0031252Cell leading edgeIEAcellular_component
GO:0031589Cell-substrate adhesionIMPbiological_process
GO:0032796Uropod organizationIBA IEAbiological_process
GO:0042102Positive regulation of T cell proliferationIEAbiological_process
GO:0042802Identical protein bindingIEAmolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043029T cell homeostasisIEAbiological_process
GO:0043234Protein complexIDAcellular_component
GO:0043548Phosphatidylinositol 3-kinase bindingIDAmolecular_function
GO:0045087Innate immune responseNASbiological_process
GO:0045335Phagocytic vesicleIDAcellular_component
GO:0048873Homeostasis of number of cells within a tissueIEAbiological_process
GO:0050918Positive chemotaxisIDAbiological_process
GO:0051015Actin filament bindingIDA IEAmolecular_function
GO:0051126Negative regulation of actin nucleationIDAbiological_process
GO:0071353Cellular response to interleukin-4IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11414852020.15267930170.69516501620.7548951952

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1271581985
GSE13712_SHEARDown-0.0278244601
GSE13712_STATICUp0.2366452870
GSE19018Up0.4490663749
GSE19899_A1Down-0.0847116851
GSE19899_A2Down-0.6960868934
PubMed_21979375_A1Down-0.2745049764
PubMed_21979375_A2Down-1.6961052440
GSE35957Down-0.0888955903
GSE36640Down-0.6389598242
GSE54402Up0.0974113088
GSE9593Up0.1422834724
GSE43922Down-0.4693259290
GSE24585Up3.0044368022
GSE37065Down-0.1071329346
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.9623624198

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-221-3pMIMAT0000278MIRT005787Western blotFunctional MTI21226887
hsa-miR-222-3pMIMAT0000279MIRT005791Western blotFunctional MTI21226887
hsa-miR-24-3pMIMAT0000080MIRT030627Western blotFunctional MTI20138800
hsa-miR-615-3pMIMAT0003283MIRT039639CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.