HCSGD entry for DMC1

1. General information

Official gene symbolDMC1
Entrez ID11144
Gene full nameDNA meiotic recombinase 1
Other gene symbolsDMC1H LIM15 dJ199H16.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0000781Chromosome, telomeric regionIEAcellular_component
GO:0000794Condensed nuclear chromosomeIEAcellular_component
GO:0001541Ovarian follicle developmentIEAbiological_process
GO:0001556Oocyte maturationIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005694ChromosomeISScellular_component
GO:0006259DNA metabolic processIEAbiological_process
GO:0007126MeiosisTASbiological_process
GO:0007129SynapsisIEAbiological_process
GO:0007131Reciprocal meiotic recombinationIEAbiological_process
GO:0007141Male meiosis IIEAbiological_process
GO:0007283SpermatogenesisTASbiological_process
GO:0007286Spermatid developmentIEAbiological_process
GO:0007292Female gamete generationTASbiological_process
GO:0008094DNA-dependent ATPase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87585430260.04005721290.99999024730.3776310530

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1881384823
GSE13712_SHEARUp0.0436427888
GSE13712_STATICDown-0.0349763324
GSE19018Down-0.1010024758
GSE19899_A1Down-0.0415703648
GSE19899_A2Down-0.0238426953
PubMed_21979375_A1Down-0.2633783549
PubMed_21979375_A2Down-0.0806881560
GSE35957Down-0.5362104711
GSE36640Down-1.3019033651
GSE54402Down-0.4279202249
GSE9593Down-0.2075557618
GSE43922Down-0.0347856967
GSE24585Up1.0033251040
GSE37065Up0.0572001173
GSE28863_A1Down-0.1082831654
GSE28863_A2Down-0.1543126535
GSE28863_A3Down-1.0821313279
GSE28863_A4Up0.2599435309
GSE48662Down-0.1903432617

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.