HCSGD entry for TBC1D8
1. General information
| Official gene symbol | TBC1D8 |
|---|---|
| Entrez ID | 11138 |
| Gene full name | TBC1 domain family, member 8 (with GRAM domain) |
| Other gene symbols | AD3 HBLP1 TBC1D8A VRP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005097 | Rab GTPase activator activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0008015 | Blood circulation | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0099293340 | 0.9140264922 | 0.2542315175 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3989301183 |
| GSE13712_SHEAR | Up | 0.1056565039 |
| GSE13712_STATIC | Down | -0.0656253360 |
| GSE19018 | Up | 0.1084501068 |
| GSE19899_A1 | Down | -0.3612889867 |
| GSE19899_A2 | Down | -0.0575563084 |
| PubMed_21979375_A1 | Up | 0.0364086750 |
| PubMed_21979375_A2 | Up | 0.8236677440 |
| GSE35957 | Down | -0.7033525975 |
| GSE36640 | Up | 0.4347992692 |
| GSE54402 | Up | 0.2332234115 |
| GSE9593 | Up | 1.1251794204 |
| GSE43922 | Up | 0.2398717303 |
| GSE24585 | Up | 0.3048043237 |
| GSE37065 | Up | 0.2853333726 |
| GSE28863_A1 | Up | 0.2932754062 |
| GSE28863_A2 | Down | -0.0787840537 |
| GSE28863_A3 | Up | 0.4752929780 |
| GSE28863_A4 | Up | 0.7702035210 |
| GSE48662 | Down | -0.0389465273 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019002 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
