HCSGD entry for FOXN3
1. General information
| Official gene symbol | FOXN3 |
|---|---|
| Entrez ID | 1112 |
| Gene full name | forkhead box N3 |
| Other gene symbols | C14orf116 CHES1 PRO1635 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000077 | DNA damage checkpoint | TAS | biological_process |
| GO:0000085 | Mitotic G2 phase | TAS | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IC IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9479368147 | 0.0272271950 | 0.9999902473 | 0.3144582018 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3760104619 |
| GSE13712_SHEAR | Down | -0.2148711565 |
| GSE13712_STATIC | Up | 0.0028068060 |
| GSE19018 | Down | -0.2906427851 |
| GSE19899_A1 | Down | -0.5624622823 |
| GSE19899_A2 | Down | -0.0620886594 |
| PubMed_21979375_A1 | Down | -1.0713482153 |
| PubMed_21979375_A2 | Down | -0.2537238537 |
| GSE35957 | Up | 0.4383818381 |
| GSE36640 | Down | -0.0737401562 |
| GSE54402 | Down | -0.6779323491 |
| GSE9593 | Up | 0.1699962308 |
| GSE43922 | Down | -0.7656110481 |
| GSE24585 | Up | 0.2942177979 |
| GSE37065 | Down | -0.1916653423 |
| GSE28863_A1 | Up | 0.1884590638 |
| GSE28863_A2 | Up | 0.2483215213 |
| GSE28863_A3 | Down | -0.1453744026 |
| GSE28863_A4 | Down | -0.0594681941 |
| GSE48662 | Down | -0.4305321630 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-574-5p | MIMAT0004795 | MIRT007196 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 23133627 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030800 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040561 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
