HCSGD entry for HIBADH
1. General information
| Official gene symbol | HIBADH |
|---|---|
| Entrez ID | 11112 |
| Gene full name | 3-hydroxyisobutyrate dehydrogenase |
| Other gene symbols | NS5ATP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004616 | Phosphogluconate dehydrogenase (decarboxylating) activity | IEA | molecular_function |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006098 | Pentose-phosphate shunt | IEA | biological_process |
| GO:0006574 | Valine catabolic process | IDA IEA | biological_process |
| GO:0008442 | 3-hydroxyisobutyrate dehydrogenase activity | IDA IEA TAS | molecular_function |
| GO:0009083 | Branched-chain amino acid catabolic process | TAS | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051287 | NAD binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9468287527 | 0.0326380229 | 0.9999902473 | 0.3407688616 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1621698126 |
| GSE13712_SHEAR | Up | 0.1581641116 |
| GSE13712_STATIC | Down | -0.0762227131 |
| GSE19018 | Up | 0.1693378459 |
| GSE19899_A1 | Down | -0.3319601133 |
| GSE19899_A2 | Down | -0.3571353728 |
| PubMed_21979375_A1 | Down | -1.6597815905 |
| PubMed_21979375_A2 | Down | -0.6539408157 |
| GSE35957 | Up | 0.0549473331 |
| GSE36640 | Down | -0.0201456242 |
| GSE54402 | Down | -0.1972214181 |
| GSE9593 | Up | 0.2566382157 |
| GSE43922 | Down | -0.4642293364 |
| GSE24585 | Down | -0.0772232154 |
| GSE37065 | Down | -0.2712696304 |
| GSE28863_A1 | Up | 0.2369198721 |
| GSE28863_A2 | Up | 0.3873276475 |
| GSE28863_A3 | Down | -0.7167118990 |
| GSE28863_A4 | Up | 0.0112139591 |
| GSE48662 | Down | -0.4672085248 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024585 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025320 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026367 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
