HCSGD entry for KATNA1
1. General information
| Official gene symbol | KATNA1 |
|---|---|
| Entrez ID | 11104 |
| Gene full name | katanin p60 (ATPase containing) subunit A 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000922 | Spindle pole | IDA | cellular_component |
| GO:0001578 | Microtubule bundle formation | IEA | biological_process |
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005811 | Lipid particle | IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005819 | Spindle | IDA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0008017 | Microtubule binding | IDA | molecular_function |
| GO:0008104 | Protein localization | IEA | biological_process |
| GO:0008568 | Microtubule-severing ATPase activity | IDA | molecular_function |
| GO:0010977 | Negative regulation of neuron projection development | IEA | biological_process |
| GO:0016887 | ATPase activity | IEA | molecular_function |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0030426 | Growth cone | IEA | cellular_component |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0031122 | Cytoplasmic microtubule organization | IEA | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0045502 | Dynein binding | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0051013 | Microtubule severing | IEA | biological_process |
| GO:0051329 | Mitotic interphase | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9446111964 | 0.0858337069 | 0.9999902473 | 0.5568718265 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1762636353 |
| GSE13712_SHEAR | Down | -0.1223422988 |
| GSE13712_STATIC | Up | 0.0042913436 |
| GSE19018 | Up | 0.1242792277 |
| GSE19899_A1 | Up | 0.0454219073 |
| GSE19899_A2 | Down | -0.1538904726 |
| PubMed_21979375_A1 | Up | 0.8203409987 |
| PubMed_21979375_A2 | Down | -0.3185416255 |
| GSE35957 | Down | -0.3093899838 |
| GSE36640 | Down | -0.3236190819 |
| GSE54402 | Up | 0.1110420253 |
| GSE9593 | Down | -0.2322856824 |
| GSE43922 | Up | 0.0662401706 |
| GSE24585 | Down | -0.2786646141 |
| GSE37065 | Down | -0.0644275274 |
| GSE28863_A1 | Down | -0.1014978395 |
| GSE28863_A2 | Up | 0.0942802492 |
| GSE28863_A3 | Down | -0.5161186991 |
| GSE28863_A4 | Down | -0.3408686809 |
| GSE48662 | Down | -0.2902694705 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002617 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002617 | Microarray | Functional MTI (Weak) | 15685193 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
