HCSGD entry for ADAMTS8
1. General information
| Official gene symbol | ADAMTS8 |
|---|---|
| Entrez ID | 11095 |
| Gene full name | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
| Other gene symbols | ADAM-TS8 METH2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005178 | Integrin binding | TAS | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006820 | Anion transport | TAS | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0008237 | Metallopeptidase activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008285 | Negative regulation of cell proliferation | TAS | biological_process |
| GO:0009673 | Low affinity phosphate transmembrane transporter activity | TAS | molecular_function |
| GO:0015698 | Inorganic anion transport | TAS | biological_process |
| GO:0031012 | Extracellular matrix | ISS | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035435 | Phosphate ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6879470917 | 0.0623421261 | 0.9999902473 | 0.4709823057 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0589791258 |
| GSE13712_SHEAR | Down | -0.0652000925 |
| GSE13712_STATIC | Down | -0.0342480305 |
| GSE19018 | Down | -2.3664044789 |
| GSE19899_A1 | Down | -0.2156860602 |
| GSE19899_A2 | Down | -1.1080174809 |
| PubMed_21979375_A1 | Down | -0.0678637485 |
| PubMed_21979375_A2 | Down | -0.0852573596 |
| GSE35957 | Up | 0.0771165044 |
| GSE36640 | Up | 1.1050135155 |
| GSE54402 | Down | -1.0382464560 |
| GSE9593 | Up | 0.1333889646 |
| GSE43922 | Up | 0.0765543619 |
| GSE24585 | Down | -0.2992785250 |
| GSE37065 | Down | -0.0638973712 |
| GSE28863_A1 | Up | 0.2462569006 |
| GSE28863_A2 | Down | -0.0632010050 |
| GSE28863_A3 | Up | 0.2928599659 |
| GSE28863_A4 | Up | 0.1410800304 |
| GSE48662 | Up | 0.1224004258 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
