HCSGD entry for ADAMTS13

1. General information

Official gene symbolADAMTS13
Entrez ID11093
Gene full nameADAM metallopeptidase with thrombospondin type 1 motif, 13
Other gene symbols13 ADAM-TS ADAM-TS13 ADAMTS-13 C9orf8 TTP VWFCP vWF-CP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005178Integrin bindingTASmolecular_function
GO:0005509Calcium ion bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005578Proteinaceous extracellular matrixTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006508ProteolysisIDAbiological_process
GO:0007160Cell-matrix adhesionNASbiological_process
GO:0007229Integrin-mediated signaling pathwayNASbiological_process
GO:0008237Metallopeptidase activityIEA TASmolecular_function
GO:0008270Zinc ion bindingTASmolecular_function
GO:0009100Glycoprotein metabolic processNASbiological_process
GO:0009986Cell surfaceNAScellular_component
GO:0016485Protein processingTASbiological_process
GO:0030168Platelet activationNASbiological_process
GO:0034341Response to interferon-gammaIEAbiological_process
GO:0034612Response to tumor necrosis factorIEAbiological_process
GO:0043171Peptide catabolic processIDAbiological_process
GO:0070670Response to interleukin-4IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.48706032830.72324578470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1029375652
GSE13712_SHEARDown-0.1975573766
GSE13712_STATICDown-0.1165625250
GSE19018Up0.1360509022
GSE19899_A1Up0.0601824086
GSE19899_A2Up0.0083818078
PubMed_21979375_A1Up0.1783455957
PubMed_21979375_A2Down-0.1212301887
GSE35957Up0.0727372001
GSE36640Up0.1788067432
GSE54402Down-0.0827692991
GSE9593Down-0.0638591721
GSE43922Up0.1223282264
GSE24585Up0.2178394425
GSE37065Up0.0093492964
GSE28863_A1Down-0.1072136614
GSE28863_A2Down-0.2776726650
GSE28863_A3Up0.3251868785
GSE28863_A4Up0.1389515433
GSE48662Up0.2206342756

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.