HCSGD entry for TRIOBP
1. General information
| Official gene symbol | TRIOBP |
|---|---|
| Entrez ID | 11078 |
| Gene full name | TRIO and F-actin binding protein |
| Other gene symbols | DFNB28 TARA dJ37E16.4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA NAS | cellular_component |
| GO:0017049 | GTP-Rho binding | NAS | molecular_function |
| GO:0030047 | Actin modification | NAS | biological_process |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0045159 | Myosin II binding | NAS | molecular_function |
| GO:0051015 | Actin filament binding | IDA | molecular_function |
| GO:0051016 | Barbed-end actin filament capping | NAS | biological_process |
| GO:1900026 | Positive regulation of substrate adhesion-dependent cell spreading | IDA IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9239642567 | 0.0986342654 | 0.9999902473 | 0.6008221477 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1871235862 |
| GSE13712_SHEAR | Up | 0.2160417702 |
| GSE13712_STATIC | Up | 0.1885887960 |
| GSE19018 | Down | -0.2440617162 |
| GSE19899_A1 | Down | -0.5068434325 |
| GSE19899_A2 | Up | 0.1246487614 |
| PubMed_21979375_A1 | Down | -0.4436436734 |
| PubMed_21979375_A2 | Down | -0.5794855941 |
| GSE35957 | Down | -0.5772233813 |
| GSE36640 | Down | -0.3927909187 |
| GSE54402 | Down | -0.4167329212 |
| GSE9593 | Up | 0.4655192512 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.1229727676 |
| GSE28863_A2 | Up | 0.0553967667 |
| GSE28863_A3 | Up | 0.0361253858 |
| GSE28863_A4 | Up | 0.1159558548 |
| GSE48662 | Down | -0.1111410950 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029872 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
