HCSGD entry for TMEM115


1. General information

Official gene symbolTMEM115
Entrez ID11070
Gene full nametransmembrane protein 115
Other gene symbolsPL6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0008285Negative regulation of cell proliferationNASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01058667600.93224651040.26155215361.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0576705169
GSE13712_SHEARUp0.0766639533
GSE13712_STATICUp0.2188533897
GSE19018Up0.2971341412
GSE19899_A1Up0.4091229973
GSE19899_A2Up1.2415265868
PubMed_21979375_A1Up1.3449341345
PubMed_21979375_A2Up1.4114556645
GSE35957Down-0.0244695121
GSE36640Up0.6774560867
GSE54402Up0.2338772911
GSE9593Up0.1940020198
GSE43922Up0.3641261402
GSE24585Down-0.3347804098
GSE37065Up0.0055030073
GSE28863_A1Up0.4030002762
GSE28863_A2Up0.0477937363
GSE28863_A3Down-0.1176020275
GSE28863_A4Down-0.2821836695
GSE48662Up0.6389346790

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-455-3pMIMAT0004784MIRT037809CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040155CLASHFunctional MTI (Weak)23622248
hsa-miR-92b-3pMIMAT0003218MIRT040622CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT051990CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.