HCSGD entry for LECT1
1. General information
| Official gene symbol | LECT1 |
|---|---|
| Entrez ID | 11061 |
| Gene full name | leukocyte cell derived chemotaxin 1 |
| Other gene symbols | BRICD3 CHM-I CHM1 MYETS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001501 | Skeletal system development | TAS | biological_process |
| GO:0001886 | Endothelial cell morphogenesis | IEA | biological_process |
| GO:0001937 | Negative regulation of endothelial cell proliferation | IEA | biological_process |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006029 | Proteoglycan metabolic process | TAS | biological_process |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016525 | Negative regulation of angiogenesis | IDA IEA | biological_process |
| GO:0030948 | Negative regulation of vascular endothelial growth factor receptor signaling pathway | IEA | biological_process |
| GO:0051216 | Cartilage development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7286952889 | 0.8312641769 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0533431698 |
| GSE13712_SHEAR | Up | 0.0220295687 |
| GSE13712_STATIC | Up | 0.0113802102 |
| GSE19018 | Up | 0.2418539348 |
| GSE19899_A1 | Down | -0.0337014540 |
| GSE19899_A2 | Up | 0.0991466623 |
| PubMed_21979375_A1 | Up | 0.0791435299 |
| PubMed_21979375_A2 | Down | -0.1698762671 |
| GSE35957 | Up | 0.1094425905 |
| GSE36640 | Up | 0.1226838446 |
| GSE54402 | Down | -0.0415793285 |
| GSE9593 | Down | -0.0009729951 |
| GSE43922 | Up | 0.0183353000 |
| GSE24585 | Down | -0.0097671716 |
| GSE37065 | Down | -0.0432393127 |
| GSE28863_A1 | Down | -0.0380721767 |
| GSE28863_A2 | Down | -0.0629878134 |
| GSE28863_A3 | Up | 0.2099524682 |
| GSE28863_A4 | Up | 0.0173022602 |
| GSE48662 | Down | -0.0294088794 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017576 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
