HCSGD entry for NUDT21
1. General information
| Official gene symbol | NUDT21 |
|---|---|
| Entrez ID | 11051 |
| Gene full name | nudix (nucleoside diphosphate linked moiety X)-type motif 21 |
| Other gene symbols | CFIM25 CPSF5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003723 | RNA binding | IDA | molecular_function |
| GO:0003729 | MRNA binding | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005849 | MRNA cleavage factor complex | IDA IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006378 | MRNA polyadenylation | IEA IMP | biological_process |
| GO:0006397 | MRNA processing | IDA | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0017091 | AU-rich element binding | IDA | molecular_function |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
| GO:0042382 | Paraspeckles | IDA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0042826 | Histone deacetylase binding | IPI | molecular_function |
| GO:0051262 | Protein tetramerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6771854337 | 0.0638799514 | 0.9999902473 | 0.4764477756 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0170029214 |
| GSE13712_SHEAR | Down | -0.0140143040 |
| GSE13712_STATIC | Down | -0.1676256294 |
| GSE19018 | Down | -0.0604146057 |
| GSE19899_A1 | Down | -0.0739584094 |
| GSE19899_A2 | Down | -0.7219333865 |
| PubMed_21979375_A1 | Down | -0.4472149399 |
| PubMed_21979375_A2 | Down | -0.9007162704 |
| GSE35957 | Down | -0.2858904222 |
| GSE36640 | Down | -1.2532141420 |
| GSE54402 | Up | 0.2345884463 |
| GSE9593 | Down | -0.4038164501 |
| GSE43922 | Down | -0.2842096554 |
| GSE24585 | Up | 0.0865618354 |
| GSE37065 | Up | 0.0070261067 |
| GSE28863_A1 | Up | 0.3763333805 |
| GSE28863_A2 | Up | 0.5413450365 |
| GSE28863_A3 | Up | 0.1701497338 |
| GSE28863_A4 | Up | 0.3099449949 |
| GSE48662 | Down | -0.7047697567 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT020022 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036074 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044405 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050609 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051764 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
