HCSGD entry for CHD1
1. General information
| Official gene symbol | CHD1 |
|---|---|
| Entrez ID | 1105 |
| Gene full name | chromodomain helicase DNA binding protein 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004003 | ATP-dependent DNA helicase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0006338 | Chromatin remodeling | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0032508 | DNA duplex unwinding | TAS | biological_process |
| GO:0035064 | Methylated histone residue binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1087937236 | 0.1881722579 | 0.6834853327 | 0.8404607906 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1419490230 |
| GSE13712_SHEAR | Up | 0.3886844388 |
| GSE13712_STATIC | Down | -0.0529766211 |
| GSE19018 | Down | -0.8231133739 |
| GSE19899_A1 | Up | 0.3331099326 |
| GSE19899_A2 | Up | 0.1301955444 |
| PubMed_21979375_A1 | Up | 0.9915413648 |
| PubMed_21979375_A2 | Up | 0.3937851912 |
| GSE35957 | Down | -0.5423397978 |
| GSE36640 | Down | -1.3934586354 |
| GSE54402 | Up | 0.3026018353 |
| GSE9593 | Down | -0.5313769798 |
| GSE43922 | Up | 0.3640573313 |
| GSE24585 | Down | -0.1387500804 |
| GSE37065 | Up | 0.2121402291 |
| GSE28863_A1 | Up | 0.5471550540 |
| GSE28863_A2 | Up | 0.7883542302 |
| GSE28863_A3 | Down | -0.0360667705 |
| GSE28863_A4 | Down | -0.2162678791 |
| GSE48662 | Down | -0.4470030984 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Epirubicin | DB00445 | APRD00361 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005127 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023406 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027799 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032461 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038317 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047842 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051818 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
