HCSGD entry for ADRM1
1. General information
| Official gene symbol | ADRM1 |
|---|---|
| Entrez ID | 11047 |
| Gene full name | adhesion regulating molecule 1 |
| Other gene symbols | ARM1 GP110 Rpn13 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000502 | Proteasome complex | IDA | cellular_component |
| GO:0002020 | Protease binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | IMP | biological_process |
| GO:0010950 | Positive regulation of endopeptidase activity | IDA | biological_process |
| GO:0010952 | Positive regulation of peptidase activity | IDA | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0043085 | Positive regulation of catalytic activity | IDA | biological_process |
| GO:0043248 | Proteasome assembly | IDA | biological_process |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
| GO:0052547 | Regulation of peptidase activity | IDA | biological_process |
| GO:0052548 | Regulation of endopeptidase activity | IDA | biological_process |
| GO:0061133 | Endopeptidase activator activity | IDA | molecular_function |
| GO:0070628 | Proteasome binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0473194901 | 0.8502427035 | 0.4812521823 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2849031559 |
| GSE13712_SHEAR | Up | 0.0053343314 |
| GSE13712_STATIC | Up | 0.0572931086 |
| GSE19018 | Down | -0.2966330600 |
| GSE19899_A1 | Up | 0.1713230351 |
| GSE19899_A2 | Up | 1.1399354653 |
| PubMed_21979375_A1 | Up | 1.7323382760 |
| PubMed_21979375_A2 | Up | 0.8949023454 |
| GSE35957 | Down | -0.2443130676 |
| GSE36640 | Up | 0.1669285471 |
| GSE54402 | Up | 0.7096818963 |
| GSE9593 | Up | 0.0423929560 |
| GSE43922 | Up | 0.2256780575 |
| GSE24585 | Down | -0.3716685665 |
| GSE37065 | Down | -0.0193789851 |
| GSE28863_A1 | Down | -0.1255596539 |
| GSE28863_A2 | Down | -0.0227490134 |
| GSE28863_A3 | Down | -0.0617444455 |
| GSE28863_A4 | Up | 0.0779905424 |
| GSE48662 | Down | -0.1377608351 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030392 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031130 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037740 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038868 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039100 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042363 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045933 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049521 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052025 | CLASH | Functional MTI (Weak) | 23622248 |
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