HCSGD entry for ADAP1

1. General information

Official gene symbolADAP1
Entrez ID11033
Gene full nameArfGAP with dual PH domains 1
Other gene symbolsCENTA1 GCS1L p42IP4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005547Phosphatidylinositol-3,4,5-trisphosphate bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0008060ARF GTPase activator activityIDA IEAmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0032312Regulation of ARF GTPase activityIEAbiological_process
GO:0043085Positive regulation of catalytic activityIDAbiological_process
GO:0043087Regulation of GTPase activityIMPbiological_process
GO:0043533Inositol 1,3,4,5 tetrakisphosphate bindingTASmolecular_function
GO:0043547Positive regulation of GTPase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67878755750.71414957260.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0756596320
GSE13712_SHEARDown-0.3538382895
GSE13712_STATICDown-0.0586459755
GSE19018Up0.1096371109
GSE19899_A1Down-0.2285915806
GSE19899_A2Up0.2351782938
PubMed_21979375_A1Down-0.0805400419
PubMed_21979375_A2Down-0.1031285313
GSE35957Up0.3602499494
GSE36640Up0.0708577131
GSE54402Up0.0613674851
GSE9593Down-0.0343902860
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.1394448512
GSE28863_A2Up0.1566251714
GSE28863_A3Down-0.1219071539
GSE28863_A4Down-0.0288120340
GSE48662Up0.1784631342

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.