HCSGD entry for KLK11


1. General information

Official gene symbolKLK11
Entrez ID11012
Gene full namekallikrein-related peptidase 11
Other gene symbolsPRSS20 TLSP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008236Serine-type peptidase activityTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80186051440.71632914020.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0303084811
GSE13712_SHEARUp0.1295857849
GSE13712_STATICDown-0.0693772337
GSE19018Down-0.0086536614
GSE19899_A1Up0.0441807055
GSE19899_A2Down-0.0777484874
PubMed_21979375_A1Down-0.0713964690
PubMed_21979375_A2Down-0.2605879376
GSE35957Up0.0361121811
GSE36640Up0.0211267440
GSE54402Down-0.0366519918
GSE9593Up0.1846517085
GSE43922Down-0.0594304858
GSE24585Up0.3163894019
GSE37065Down-0.1328889899
GSE28863_A1Down-0.0101188273
GSE28863_A2Down-0.0251229003
GSE28863_A3Up0.2171455634
GSE28863_A4Up0.0545957463
GSE48662Up0.0146176268

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017931MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.