HCSGD entry for SLC27A2
1. General information
| Official gene symbol | SLC27A2 |
|---|---|
| Entrez ID | 11001 |
| Gene full name | solute carrier family 27 (fatty acid transporter), member 2 |
| Other gene symbols | ACSVL1 FACVL1 FATP2 HsT17226 VLACS VLCS hFACVL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001561 | Fatty acid alpha-oxidation | IDA TAS | biological_process |
| GO:0001676 | Long-chain fatty acid metabolic process | IDA | biological_process |
| GO:0004467 | Long-chain fatty acid-CoA ligase activity | IDA IEA | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005777 | Peroxisome | IEA | cellular_component |
| GO:0005778 | Peroxisomal membrane | IDA TAS | cellular_component |
| GO:0005779 | Integral component of peroxisomal membrane | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IDA TAS | cellular_component |
| GO:0006635 | Fatty acid beta-oxidation | IDA | biological_process |
| GO:0006699 | Bile acid biosynthetic process | IDA TAS | biological_process |
| GO:0008206 | Bile acid metabolic process | TAS | biological_process |
| GO:0015245 | Fatty acid transporter activity | IEA | molecular_function |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0031957 | Very long-chain fatty acid-CoA ligase activity | IDA IEA | molecular_function |
| GO:0042760 | Very long-chain fatty acid catabolic process | IEA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0044539 | Long-chain fatty acid import | IDA | biological_process |
| GO:0050197 | Phytanate-CoA ligase activity | IDA | molecular_function |
| GO:0070251 | Pristanate-CoA ligase activity | IDA | molecular_function |
| GO:0097089 | Methyl-branched fatty acid metabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9059286159 | 0.3329210250 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1125191431 |
| GSE13712_SHEAR | Down | -0.0609718094 |
| GSE13712_STATIC | Up | 0.0665251544 |
| GSE19018 | Up | 0.0948190861 |
| GSE19899_A1 | Up | 0.1018391837 |
| GSE19899_A2 | Up | 0.0092927699 |
| PubMed_21979375_A1 | Up | 0.0267607992 |
| PubMed_21979375_A2 | Up | 0.0976255130 |
| GSE35957 | Up | 0.1300436141 |
| GSE36640 | Down | -0.0203122171 |
| GSE54402 | Down | -0.1603029908 |
| GSE9593 | Down | -0.0958594055 |
| GSE43922 | Up | 0.0136828369 |
| GSE24585 | Down | -0.6729791055 |
| GSE37065 | Down | -0.0315526914 |
| GSE28863_A1 | Down | -0.0482602450 |
| GSE28863_A2 | Up | 0.0850736611 |
| GSE28863_A3 | Down | -0.3867436851 |
| GSE28863_A4 | Down | -0.0924949241 |
| GSE48662 | Down | -0.1160390819 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020494 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032206 | Proteomics | Functional MTI (Weak) | 18668040 |
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