HCSGD entry for GCN1L1
1. General information
| Official gene symbol | GCN1L1 |
|---|---|
| Entrez ID | 10985 |
| Gene full name | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) |
| Other gene symbols | GCN1 GCN1L PRIC295 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IDA NAS | cellular_component |
| GO:0005840 | Ribosome | NAS | cellular_component |
| GO:0006412 | Translation | NAS | biological_process |
| GO:0006417 | Regulation of translation | IEA | biological_process |
| GO:0008135 | Translation factor activity, nucleic acid binding | NAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0199360929 | 0.9037148741 | 0.3420716428 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0355052305 |
| GSE13712_SHEAR | Up | 0.6847937170 |
| GSE13712_STATIC | Up | 0.4900556142 |
| GSE19018 | Up | 0.1090787035 |
| GSE19899_A1 | Up | 0.1907427537 |
| GSE19899_A2 | Down | -0.2002787273 |
| PubMed_21979375_A1 | Up | 0.7155677188 |
| PubMed_21979375_A2 | Up | 1.0307554371 |
| GSE35957 | Down | -0.1445815620 |
| GSE36640 | Up | 0.1769288220 |
| GSE54402 | Up | 0.2002621264 |
| GSE9593 | Down | -0.3409924958 |
| GSE43922 | Up | 0.1431688489 |
| GSE24585 | Down | -0.1610234560 |
| GSE37065 | Down | -0.3874316077 |
| GSE28863_A1 | Up | 1.4118552762 |
| GSE28863_A2 | Up | 1.2105898071 |
| GSE28863_A3 | Down | -0.1117828712 |
| GSE28863_A4 | Down | -0.0024619620 |
| GSE48662 | Up | 0.0120266540 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1293 | MIMAT0005883 | MIRT035903 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036502 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040858 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042010 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-3p | MIMAT0001343 | MIRT042433 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042534 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043819 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045354 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045622 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046637 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046958 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052324 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052425 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
