HCSGD entry for CLP1
1. General information
| Official gene symbol | CLP1 |
|---|---|
| Entrez ID | 10978 |
| Gene full name | cleavage and polyadenylation factor I subunit 1 |
| Other gene symbols | HEAB hClp1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000214 | TRNA-intron endonuclease complex | IDA IEA | cellular_component |
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0005524 | ATP binding | IEA TAS | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005849 | MRNA cleavage factor complex | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006388 | TRNA splicing, via endonucleolytic cleavage and ligation | IDA IEA | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030423 | Targeting of mRNA for destruction involved in RNA interference | IMP | biological_process |
| GO:0031124 | MRNA 3'-end processing | IEA TAS | biological_process |
| GO:0035087 | SiRNA loading onto RISC involved in RNA interference | IDA IEA | biological_process |
| GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity | IEA | molecular_function |
| GO:0051733 | Polydeoxyribonucleotide kinase activity | IDA | molecular_function |
| GO:0051736 | ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity | IDA IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0511189393 | 0.9072760913 | 0.4953465587 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3966108578 |
| GSE13712_SHEAR | Up | 0.0532315822 |
| GSE13712_STATIC | Up | 0.0928308981 |
| GSE19018 | Down | -0.0280488921 |
| GSE19899_A1 | Up | 0.6572798520 |
| GSE19899_A2 | Up | 0.5374687314 |
| PubMed_21979375_A1 | Up | 1.1298626954 |
| PubMed_21979375_A2 | Up | 0.5239764659 |
| GSE35957 | Down | -0.0657593993 |
| GSE36640 | Down | -0.0959010507 |
| GSE54402 | Up | 0.3284278815 |
| GSE9593 | Down | -0.0074467156 |
| GSE43922 | Up | 0.7808250434 |
| GSE24585 | Down | -0.0593176921 |
| GSE37065 | Up | 0.0807968573 |
| GSE28863_A1 | Down | -0.0690733612 |
| GSE28863_A2 | Down | -0.0194597771 |
| GSE28863_A3 | Down | -0.4669153083 |
| GSE28863_A4 | Up | 0.1241465041 |
| GSE48662 | Down | -0.5002119026 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027594 | Microarray | Functional MTI (Weak) | 19088304 |
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