HCSGD entry for CLP1


1. General information

Official gene symbolCLP1
Entrez ID10978
Gene full namecleavage and polyadenylation factor I subunit 1
Other gene symbolsHEAB hClp1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000214TRNA-intron endonuclease complexIDA IEAcellular_component
GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0005524ATP bindingIEA TASmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005849MRNA cleavage factor complexIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006369Termination of RNA polymerase II transcriptionTASbiological_process
GO:0006388TRNA splicing, via endonucleolytic cleavage and ligationIDA IEAbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0030423Targeting of mRNA for destruction involved in RNA interferenceIMPbiological_process
GO:0031124MRNA 3'-end processingIEA TASbiological_process
GO:0035087SiRNA loading onto RISC involved in RNA interferenceIDA IEAbiological_process
GO:0046404ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activityIEAmolecular_function
GO:0051733Polydeoxyribonucleotide kinase activityIDAmolecular_function
GO:0051736ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activityIDA IEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05111893930.90727609130.49534655871.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3966108578
GSE13712_SHEARUp0.0532315822
GSE13712_STATICUp0.0928308981
GSE19018Down-0.0280488921
GSE19899_A1Up0.6572798520
GSE19899_A2Up0.5374687314
PubMed_21979375_A1Up1.1298626954
PubMed_21979375_A2Up0.5239764659
GSE35957Down-0.0657593993
GSE36640Down-0.0959010507
GSE54402Up0.3284278815
GSE9593Down-0.0074467156
GSE43922Up0.7808250434
GSE24585Down-0.0593176921
GSE37065Up0.0807968573
GSE28863_A1Down-0.0690733612
GSE28863_A2Down-0.0194597771
GSE28863_A3Down-0.4669153083
GSE28863_A4Up0.1241465041
GSE48662Down-0.5002119026

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027594MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.