HCSGD entry for TMED10
1. General information
| Official gene symbol | TMED10 |
|---|---|
| Entrez ID | 10972 |
| Gene full name | transmembrane emp24-like trafficking protein 10 (yeast) |
| Other gene symbols | P24(DELTA) S31I125 S31III125 TMP21 Tmp-21-I p23 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IDA TAS | cellular_component |
| GO:0001101 | Response to acid | IEA | biological_process |
| GO:0001822 | Kidney development | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005793 | Endoplasmic reticulum-Golgi intermediate compartment | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005801 | Cis-Golgi network | ISS | cellular_component |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0006886 | Intracellular protein transport | IDA | biological_process |
| GO:0006888 | ER to Golgi vesicle-mediated transport | TAS | biological_process |
| GO:0006890 | Retrograde vesicle-mediated transport, Golgi to ER | ISS | biological_process |
| GO:0007030 | Golgi organization | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA ISS | cellular_component |
| GO:0019905 | Syntaxin binding | IPI | molecular_function |
| GO:0030137 | COPI-coated vesicle | ISS | cellular_component |
| GO:0030140 | Trans-Golgi network transport vesicle | ISS | cellular_component |
| GO:0030658 | Transport vesicle membrane | IEA | cellular_component |
| GO:0030667 | Secretory granule membrane | ISS | cellular_component |
| GO:0032403 | Protein complex binding | IEA | molecular_function |
| GO:0033116 | Endoplasmic reticulum-Golgi intermediate compartment membrane | IEA | cellular_component |
| GO:0034205 | Beta-amyloid formation | IMP | biological_process |
| GO:0035459 | Cargo loading into vesicle | TAS | biological_process |
| GO:0035964 | COPI-coated vesicle budding | IDA | biological_process |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0042589 | Zymogen granule membrane | ISS | cellular_component |
| GO:0043279 | Response to alkaloid | IEA | biological_process |
| GO:0045055 | Regulated secretory pathway | ISS | biological_process |
| GO:0048199 | Vesicle targeting, to, from or within Golgi | ISS | biological_process |
| GO:0048205 | COPI coating of Golgi vesicle | TAS | biological_process |
| GO:0048208 | COPII vesicle coating | TAS | biological_process |
| GO:0051259 | Protein oligomerization | IEA | biological_process |
| GO:0070765 | Gamma-secretase complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8552838152 | 0.3303777136 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1001838209 |
| GSE13712_SHEAR | Down | -0.0486016939 |
| GSE13712_STATIC | Up | 0.0110178430 |
| GSE19018 | Up | 0.4595832225 |
| GSE19899_A1 | Down | -0.2985788400 |
| GSE19899_A2 | Down | -0.0319991387 |
| PubMed_21979375_A1 | Down | -0.3713038214 |
| PubMed_21979375_A2 | Down | -0.2172103363 |
| GSE35957 | Up | 0.0097860268 |
| GSE36640 | Up | 0.0623350465 |
| GSE54402 | Down | -0.1344796747 |
| GSE9593 | Up | 0.1037450636 |
| GSE43922 | Down | -0.0663845959 |
| GSE24585 | Up | 0.1453577807 |
| GSE37065 | Up | 0.1410373283 |
| GSE28863_A1 | Down | -0.2049162398 |
| GSE28863_A2 | Up | 0.1085309792 |
| GSE28863_A3 | Down | -0.5508413113 |
| GSE28863_A4 | Down | -0.0049361455 |
| GSE48662 | Down | -0.0771916551 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005139 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022632 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024306 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025755 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026497 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050886 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
