HCSGD entry for YWHAQ
1. General information
| Official gene symbol | YWHAQ |
|---|---|
| Entrez ID | 10971 |
| Gene full name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide |
| Other gene symbols | 14-3-3 1C5 HS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006605 | Protein targeting | IEA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | TAS | cellular_component |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
| GO:0070062 | Extracellular vesicular exosome | IDA | cellular_component |
| GO:0071889 | 14-3-3 protein binding | IEA | molecular_function |
| GO:0097193 | Intrinsic apoptotic signaling pathway | TAS | biological_process |
| GO:1900740 | Positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9145998442 | 0.2303836936 | 0.9999902473 | 0.9243794512 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1433784412 |
| GSE13712_SHEAR | Up | 0.0611929663 |
| GSE13712_STATIC | Up | 0.0359769322 |
| GSE19018 | Up | 0.2785354464 |
| GSE19899_A1 | Down | -0.0917064990 |
| GSE19899_A2 | Down | -0.1437118642 |
| PubMed_21979375_A1 | Down | -0.2784958733 |
| PubMed_21979375_A2 | Down | -0.2536305957 |
| GSE35957 | Down | -0.0109959333 |
| GSE36640 | Down | -0.2287473411 |
| GSE54402 | Down | -0.0405134432 |
| GSE9593 | Up | 0.0016575733 |
| GSE43922 | Down | -0.0826602170 |
| GSE24585 | Down | -0.2821359367 |
| GSE37065 | Up | 0.0603119227 |
| GSE28863_A1 | Up | 0.0258719256 |
| GSE28863_A2 | Up | 0.4593294693 |
| GSE28863_A3 | Down | -0.4733050230 |
| GSE28863_A4 | Down | -0.0952196136 |
| GSE48662 | Down | -0.4572488548 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001321 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-214-3p | MIMAT0000271 | MIRT024964 | Microarray;Other | Functional MTI (Weak) | 19859982 |
| hsa-miR-1910-5p | MIMAT0007884 | MIRT035800 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041385 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-424-5p | MIMAT0001341 | MIRT042441 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042637 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043806 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048886 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049225 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051373 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051526 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
