HCSGD entry for PNRC1
1. General information
| Official gene symbol | PNRC1 |
|---|---|
| Entrez ID | 10957 |
| Gene full name | proline-rich nuclear receptor coactivator 1 |
| Other gene symbols | B4-2 PNAS-145 PROL2 PRR2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0256850994 | 0.6688679419 | 0.3755875000 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0425532338 |
| GSE13712_SHEAR | Down | -0.2612773147 |
| GSE13712_STATIC | Down | -0.3960269124 |
| GSE19018 | Up | 1.5475707274 |
| GSE19899_A1 | Down | -0.0566037114 |
| GSE19899_A2 | Up | 0.2936721124 |
| PubMed_21979375_A1 | Down | -0.1548400216 |
| PubMed_21979375_A2 | Up | 0.3142856050 |
| GSE35957 | Up | 0.1558826472 |
| GSE36640 | Up | 0.7487839526 |
| GSE54402 | Down | -0.1536785003 |
| GSE9593 | Up | 0.4737156773 |
| GSE43922 | Up | 0.0226271612 |
| GSE24585 | Up | 0.4552229251 |
| GSE37065 | Up | 0.1821619393 |
| GSE28863_A1 | Up | 0.5742412267 |
| GSE28863_A2 | Up | 0.5563803463 |
| GSE28863_A3 | Up | 0.1036256565 |
| GSE28863_A4 | Down | -0.3817077147 |
| GSE48662 | Up | 0.1557779606 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016955 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027450 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-1250-5p | MIMAT0005902 | MIRT035862 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038076 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048540 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052482 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
