HCSGD entry for SF3A3
1. General information
| Official gene symbol | SF3A3 |
|---|---|
| Entrez ID | 10946 |
| Gene full name | splicing factor 3a, subunit 3, 60kDa |
| Other gene symbols | PRP9 PRPF9 SAP61 SF3a60 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000375 | RNA splicing, via transesterification reactions | TAS | biological_process |
| GO:0000389 | MRNA 3'-splice site recognition | TAS | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006397 | MRNA processing | IMP | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9259275066 | 0.0367673759 | 0.9999902473 | 0.3613259328 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0164776071 |
| GSE13712_SHEAR | Down | -0.3536389858 |
| GSE13712_STATIC | Up | 0.1771581055 |
| GSE19018 | Down | -0.3139076792 |
| GSE19899_A1 | Down | -0.4740042089 |
| GSE19899_A2 | Down | -0.4938171788 |
| PubMed_21979375_A1 | Down | -0.9138878569 |
| PubMed_21979375_A2 | Down | -0.1312446900 |
| GSE35957 | Down | -0.4741190096 |
| GSE36640 | Down | -1.2123539597 |
| GSE54402 | Down | -0.0432871763 |
| GSE9593 | Down | -0.4859100969 |
| GSE43922 | Down | -0.0131802470 |
| GSE24585 | Down | -0.2403403357 |
| GSE37065 | Up | 0.0686595643 |
| GSE28863_A1 | Up | 0.4441173213 |
| GSE28863_A2 | Up | 0.5633840064 |
| GSE28863_A3 | Down | -0.1966674212 |
| GSE28863_A4 | Up | 0.0640509308 |
| GSE48662 | Down | -0.1122840565 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027169 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031847 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040150 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049556 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
