HCSGD entry for PRSS21
1. General information
| Official gene symbol | PRSS21 |
|---|---|
| Entrez ID | 10942 |
| Gene full name | protease, serine, 21 (testisin) |
| Other gene symbols | ESP-1 ESP1 TEST1 TESTISIN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008236 | Serine-type peptidase activity | TAS | molecular_function |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2298328863 | 0.9195662969 | 0.9128461446 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0372220069 |
| GSE13712_SHEAR | Up | 0.1828895837 |
| GSE13712_STATIC | Up | 0.1556512864 |
| GSE19018 | Up | 0.2421420231 |
| GSE19899_A1 | Up | 0.0008185135 |
| GSE19899_A2 | Up | 0.1312840113 |
| PubMed_21979375_A1 | Up | 0.3179187141 |
| PubMed_21979375_A2 | Down | -0.0440970732 |
| GSE35957 | Up | 0.3283855140 |
| GSE36640 | Up | 0.0031847416 |
| GSE54402 | Down | -0.0130742342 |
| GSE9593 | Down | -0.1848356865 |
| GSE43922 | Up | 0.0845814517 |
| GSE24585 | Up | 0.0195111362 |
| GSE37065 | Down | -0.0312987730 |
| GSE28863_A1 | Up | 0.0166467673 |
| GSE28863_A2 | Down | -0.0363196664 |
| GSE28863_A3 | Up | 0.5788706866 |
| GSE28863_A4 | Up | 0.0781375381 |
| GSE48662 | Down | -0.0164055433 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001346 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT021022 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
