HCSGD entry for AFG3L2

1. General information

Official gene symbolAFG3L2
Entrez ID10939
Gene full nameAFG3 ATPase family member 3-like 2 (S. cerevisiae)
Other gene symbolsSCA28 SPAX5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007409AxonogenesisIEAbiological_process
GO:0007528Neuromuscular junction developmentIEAbiological_process
GO:0008053Mitochondrial fusionIEAbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0017111Nucleoside-triphosphatase activityIEAmolecular_function
GO:0021675Nerve developmentIEAbiological_process
GO:0034982Mitochondrial protein processingIEAbiological_process
GO:0040014Regulation of multicellular organism growthIEAbiological_process
GO:0042407Cristae formationIEAbiological_process
GO:0042552MyelinationIEAbiological_process
GO:0048747Muscle fiber developmentIEAbiological_process
GO:0051082Unfolded protein bindingTASmolecular_function
GO:0060013Righting reflexIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27814306830.94248308950.97517804551.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2056790974
GSE13712_SHEARUp0.0723290153
GSE13712_STATICUp0.0471155892
GSE19018Down-0.2752172911
GSE19899_A1Up0.0397925222
GSE19899_A2Up0.5262470030
PubMed_21979375_A1Up0.2492479771
PubMed_21979375_A2Up0.3400220137
GSE35957Up0.0706066556
GSE36640Down-0.2098266359
GSE54402Up0.1131549982
GSE9593Down-0.1257116403
GSE43922Up0.1914783729
GSE24585Down-0.0205646556
GSE37065Up0.0239903780
GSE28863_A1Up0.1641353630
GSE28863_A2Up0.1690424242
GSE28863_A3Up0.0732476716
GSE28863_A4Up0.0881940033
GSE48662Down-0.1077961207

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Adenosine triphosphateDB00171 NUTR00017 | EXPT00007

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031837ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.