HCSGD entry for UTS2

1. General information

Official gene symbolUTS2
Entrez ID10911
Gene full nameurotensin 2
Other gene symbolsPRO1068 U-II UCN2 UII
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIEAbiological_process
GO:0003105Negative regulation of glomerular filtrationIEAbiological_process
GO:0005102Receptor bindingTASmolecular_function
GO:0005179Hormone activityIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006936Muscle contractionTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008217Regulation of blood pressureTASbiological_process
GO:0010459Negative regulation of heart rateIEAbiological_process
GO:0010460Positive regulation of heart rateIEAbiological_process
GO:0010763Positive regulation of fibroblast migrationIEAbiological_process
GO:0010841Positive regulation of circadian sleep/wake cycle, wakefulnessIEAbiological_process
GO:0032224Positive regulation of synaptic transmission, cholinergicIEAbiological_process
GO:0032967Positive regulation of collagen biosynthetic processIEAbiological_process
GO:0033574Response to testosteroneIEAbiological_process
GO:0035811Negative regulation of urine volumeIEAbiological_process
GO:0035814Negative regulation of renal sodium excretionIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0045597Positive regulation of cell differentiationIEAbiological_process
GO:0045766Positive regulation of angiogenesisIEAbiological_process
GO:0045776Negative regulation of blood pressureIEAbiological_process
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0045909Positive regulation of vasodilationIEAbiological_process
GO:0046005Positive regulation of circadian sleep/wake cycle, REM sleepIEAbiological_process
GO:0046676Negative regulation of insulin secretionIEAbiological_process
GO:0048146Positive regulation of fibroblast proliferationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65620354850.59579423270.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0391803107
GSE13712_SHEARDown-0.0204529986
GSE13712_STATICDown-0.0220848585
GSE19018Up0.1990809123
GSE19899_A1Up0.1642102995
GSE19899_A2Down-0.1102934558
PubMed_21979375_A1Up0.2707922066
PubMed_21979375_A2Up0.1745767572
GSE35957Up0.1320015516
GSE36640Up0.0401687749
GSE54402Up0.1013198294
GSE9593Up0.0827483467
GSE43922Up0.0216926083
GSE24585Up0.1914039992
GSE37065Down-0.0978851074
GSE28863_A1Down-0.4386808480
GSE28863_A2Down-0.2285626982
GSE28863_A3Up0.0837865332
GSE28863_A4Down-0.0641051203
GSE48662Down-0.0624660445

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018692MicroarrayFunctional MTI (Weak)18185580
hsa-miR-148b-3pMIMAT0000759MIRT019441MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.