HCSGD entry for MMP24
1. General information
| Official gene symbol | MMP24 |
|---|---|
| Entrez ID | 10893 |
| Gene full name | matrix metallopeptidase 24 (membrane-inserted) |
| Other gene symbols | MMP-24 MMP25 MT-MMP 5 MT-MMP5 MT5-MMP MT5MMP MTMMP5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008047 | Enzyme activator activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5104673379 | 0.5223861062 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0013271473 |
| GSE13712_SHEAR | Down | -0.4478817586 |
| GSE13712_STATIC | Down | -0.0896771905 |
| GSE19018 | Down | -0.0979870846 |
| GSE19899_A1 | Down | -0.0283308262 |
| GSE19899_A2 | Up | 0.2058014813 |
| PubMed_21979375_A1 | Up | 0.5354472034 |
| PubMed_21979375_A2 | Up | 0.0751145444 |
| GSE35957 | Up | 0.3936675735 |
| GSE36640 | Up | 0.5827797453 |
| GSE54402 | Up | 0.2844643692 |
| GSE9593 | Up | 0.1081147663 |
| GSE43922 | Up | 0.0156530192 |
| GSE24585 | Down | -0.0271446297 |
| GSE37065 | Down | -0.1889007281 |
| GSE28863_A1 | Down | -0.4408646338 |
| GSE28863_A2 | Up | 0.0870443614 |
| GSE28863_A3 | Down | -0.0046970741 |
| GSE28863_A4 | Down | -0.1927084459 |
| GSE48662 | Up | 0.2169816135 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Marimastat | DB00786 | APRD00559 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29b-3p | MIMAT0000100 | MIRT005385 | Luciferase reporter assay//qRT-PCR | Functional MTI | 21305051 |
| hsa-miR-29c-3p | MIMAT0000681 | MIRT005386 | Luciferase reporter assay//qRT-PCR | Functional MTI | 21305051 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
