HCSGD entry for NMU
1. General information
| Official gene symbol | NMU |
|---|---|
| Entrez ID | 10874 |
| Gene full name | neuromedin U |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001696 | Gastric acid secretion | IEA | biological_process |
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0006940 | Regulation of smooth muscle contraction | IEA TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007218 | Neuropeptide signaling pathway | IEA | biological_process |
| GO:0007586 | Digestion | TAS | biological_process |
| GO:0009648 | Photoperiodism | IEA | biological_process |
| GO:0019233 | Sensory perception of pain | IEA | biological_process |
| GO:0042755 | Eating behavior | IEA | biological_process |
| GO:0042922 | Neuromedin U receptor binding | IEA | molecular_function |
| GO:0043195 | Terminal bouton | IEA | cellular_component |
| GO:0045987 | Positive regulation of smooth muscle contraction | IEA | biological_process |
| GO:0046887 | Positive regulation of hormone secretion | IEA | biological_process |
| GO:0050806 | Positive regulation of synaptic transmission | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1268464420 | 0.8854252650 | 0.7256204733 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0258078848 |
| GSE13712_SHEAR | Up | 0.1714139440 |
| GSE13712_STATIC | Up | 1.3590299470 |
| GSE19018 | Up | 0.2230633892 |
| GSE19899_A1 | Up | 0.1265936769 |
| GSE19899_A2 | Down | -0.0111777654 |
| PubMed_21979375_A1 | Up | 0.2311890781 |
| PubMed_21979375_A2 | Up | 0.3541851238 |
| GSE35957 | Down | -0.5466954436 |
| GSE36640 | Down | -0.2572236909 |
| GSE54402 | Down | -0.2469280145 |
| GSE9593 | Up | 0.2160588227 |
| GSE43922 | Up | 0.0679831677 |
| GSE24585 | Down | -0.0337256194 |
| GSE37065 | Up | 0.0070308734 |
| GSE28863_A1 | Up | 0.0326045006 |
| GSE28863_A2 | Down | -0.0095674541 |
| GSE28863_A3 | Up | 0.3535570901 |
| GSE28863_A4 | Up | 0.0866911584 |
| GSE48662 | Down | -0.2030133205 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024550 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026774 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26206128 | Other tumor initiators, methyl methanesulfonate (MMS) and N-methyl-N-nitrosourea (NMU), did not reveal apparent differences in cytotoxicity between wild-type and p53-deficient ES cells |
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