HCSGD entry for ME3
1. General information
| Official gene symbol | ME3 |
|---|---|
| Entrez ID | 10873 |
| Gene full name | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| Other gene symbols | NADP-ME |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004470 | Malic enzyme activity | IDA | molecular_function |
| GO:0004471 | Malate dehydrogenase (decarboxylating) (NAD+) activity | IEA | molecular_function |
| GO:0004473 | Malate dehydrogenase (decarboxylating) (NADP+) activity | IDA | molecular_function |
| GO:0005739 | Mitochondrion | IEA TAS | cellular_component |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0006090 | Pyruvate metabolic process | IDA | biological_process |
| GO:0006108 | Malate metabolic process | IDA IEA | biological_process |
| GO:0008948 | Oxaloacetate decarboxylase activity | IEA | molecular_function |
| GO:0009060 | Aerobic respiration | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048037 | Cofactor binding | TAS | molecular_function |
| GO:0051287 | NAD binding | IEA | molecular_function |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
| GO:0072592 | Oxygen metabolic process | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6439480643 | 0.6259816116 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1732395743 |
| GSE13712_SHEAR | Down | -0.1234832338 |
| GSE13712_STATIC | Up | 0.2480618722 |
| GSE19018 | Up | 0.1345976822 |
| GSE19899_A1 | Up | 0.0462304621 |
| GSE19899_A2 | Down | -0.0729325066 |
| PubMed_21979375_A1 | Down | -0.1901237728 |
| PubMed_21979375_A2 | Up | 0.2291869464 |
| GSE35957 | Down | -0.2003557472 |
| GSE36640 | Down | -0.1116504414 |
| GSE54402 | Down | -0.1243948249 |
| GSE9593 | Up | 0.3109218925 |
| GSE43922 | Up | 0.0488658687 |
| GSE24585 | Up | 0.2016308609 |
| GSE37065 | Down | -0.0859073765 |
| GSE28863_A1 | Down | -0.0619400468 |
| GSE28863_A2 | Up | 0.0733427897 |
| GSE28863_A3 | Down | -0.0243178271 |
| GSE28863_A4 | Up | 0.1023173676 |
| GSE48662 | Up | 0.0039216192 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
| Tartronate | DB03680 | EXPT03129 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028648 | Proteomics | Functional MTI (Weak) | 18668040 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
