HCSGD entry for USP19
1. General information
| Official gene symbol | USP19 |
|---|---|
| Entrez ID | 10869 |
| Gene full name | ubiquitin specific peptidase 19 |
| Other gene symbols | ZMYND9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004221 | Ubiquitin thiolesterase activity | IEA | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IEA | molecular_function |
| GO:0014732 | Skeletal muscle atrophy | ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016579 | Protein deubiquitination | ISS | biological_process |
| GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0031647 | Regulation of protein stability | ISS | biological_process |
| GO:0034976 | Response to endoplasmic reticulum stress | IEP | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048642 | Negative regulation of skeletal muscle tissue development | ISS | biological_process |
| GO:0090068 | Positive regulation of cell cycle process | ISS | biological_process |
| GO:1900037 | Regulation of cellular response to hypoxia | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6337357813 | 0.5699123931 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0600390005 |
| GSE13712_SHEAR | Up | 0.0156567516 |
| GSE13712_STATIC | Down | -0.0844899195 |
| GSE19018 | Up | 0.0705753031 |
| GSE19899_A1 | Down | -0.0721914418 |
| GSE19899_A2 | Up | 0.1287221585 |
| PubMed_21979375_A1 | Down | -0.1775863556 |
| PubMed_21979375_A2 | Up | 0.1846513210 |
| GSE35957 | Down | -0.2782566945 |
| GSE36640 | Up | 0.1104242966 |
| GSE54402 | Up | 0.0635162604 |
| GSE9593 | Down | -0.1547267224 |
| GSE43922 | Down | -0.0036513678 |
| GSE24585 | Up | 0.0530802331 |
| GSE37065 | Down | -0.0637932995 |
| GSE28863_A1 | Up | 0.4661451559 |
| GSE28863_A2 | Up | 0.3041568352 |
| GSE28863_A3 | Down | -0.3858417456 |
| GSE28863_A4 | Down | -0.2758553179 |
| GSE48662 | Up | 0.1670218014 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040472 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045286 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047096 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048191 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
