HCSGD entry for FTCD
1. General information
| Official gene symbol | FTCD |
|---|---|
| Entrez ID | 10841 |
| Gene full name | formiminotransferase cyclodeaminase |
| Other gene symbols | LCHC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005542 | Folic acid binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005814 | Centriole | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006548 | Histidine catabolic process | TAS | biological_process |
| GO:0006760 | Folic acid-containing compound metabolic process | TAS | biological_process |
| GO:0007010 | Cytoskeleton organization | IEA | biological_process |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0019556 | Histidine catabolic process to glutamate and formamide | IEA | biological_process |
| GO:0019557 | Histidine catabolic process to glutamate and formate | IEA | biological_process |
| GO:0030409 | Glutamate formimidoyltransferase activity | IEA | molecular_function |
| GO:0030412 | Formimidoyltetrahydrofolate cyclodeaminase activity | EXP | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0035999 | Tetrahydrofolate interconversion | IEA | biological_process |
| GO:0044237 | Cellular metabolic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4405198511 | 0.9373558034 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0026380970 |
| GSE13712_SHEAR | Up | 0.1826613737 |
| GSE13712_STATIC | Down | -0.0019326796 |
| GSE19018 | Up | 0.0761941349 |
| GSE19899_A1 | Up | 0.0343695027 |
| GSE19899_A2 | Up | 0.0991783518 |
| PubMed_21979375_A1 | Down | -0.0296355757 |
| PubMed_21979375_A2 | Up | 0.0360200697 |
| GSE35957 | Up | 0.1605987107 |
| GSE36640 | Up | 0.0857132205 |
| GSE54402 | Up | 0.0150836301 |
| GSE9593 | Up | 0.0484947140 |
| GSE43922 | Up | 0.0372111709 |
| GSE24585 | Up | 0.0691861932 |
| GSE37065 | Down | -0.0481755059 |
| GSE28863_A1 | Down | -0.1358507471 |
| GSE28863_A2 | Down | -0.0484972813 |
| GSE28863_A3 | Up | 0.4076573071 |
| GSE28863_A4 | Up | 0.2696950865 |
| GSE48662 | Down | -0.0374600281 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018835 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
