HCSGD entry for NEU3
1. General information
| Official gene symbol | NEU3 |
|---|---|
| Entrez ID | 10825 |
| Gene full name | sialidase 3 (membrane sialidase) |
| Other gene symbols | SIAL3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004308 | Exo-alpha-sialidase activity | IDA IEA | molecular_function |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IDA | biological_process |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006687 | Glycosphingolipid metabolic process | TAS | biological_process |
| GO:0006689 | Ganglioside catabolic process | IDA | biological_process |
| GO:0009313 | Oligosaccharide catabolic process | IDA | biological_process |
| GO:0016997 | Alpha-sialidase activity | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0052794 | Exo-alpha-(2->3)-sialidase activity | ISS | molecular_function |
| GO:0052795 | Exo-alpha-(2->6)-sialidase activity | IEA | molecular_function |
| GO:0052796 | Exo-alpha-(2->8)-sialidase activity | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5119137039 | 0.8090267543 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0089240898 |
| GSE13712_SHEAR | Up | 0.0061945105 |
| GSE13712_STATIC | Down | -0.0315425665 |
| GSE19018 | Up | 0.1233035819 |
| GSE19899_A1 | Up | 0.0061441355 |
| GSE19899_A2 | Up | 0.0695195120 |
| PubMed_21979375_A1 | Up | 0.0249721020 |
| PubMed_21979375_A2 | Up | 0.3506273155 |
| GSE35957 | Up | 0.0267769890 |
| GSE36640 | Down | -0.3144919530 |
| GSE54402 | Down | -0.3164776158 |
| GSE9593 | Down | -0.1688598435 |
| GSE43922 | Up | 0.4491274583 |
| GSE24585 | Up | 0.1701923720 |
| GSE37065 | Down | -0.1474673019 |
| GSE28863_A1 | Up | 0.1675136169 |
| GSE28863_A2 | Up | 0.2493758342 |
| GSE28863_A3 | Down | -0.2064179634 |
| GSE28863_A4 | Up | 0.1146821560 |
| GSE48662 | Up | 0.0473181187 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036294 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052460 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
